January 18, 2022 0 Comments

The dosage of Modafinil is one of the biggest questions that people have when they are considering using Modafinil for cognitive enhancement. The Modafinil doses you should be taking depend on many factors, including your age and weight. In this post, we will go over how to determine what Modafinil dose might work best for you!

What is Modafinil?

The Modafinil pill, usually taken every day at night, is a psychostimulant that improves wakefulness and attention. Let’s take a look at what this smart drug does and why so many people appear to strongly prefer it.

Modafinil (brand name: Provigil) is a wakefulness medication that’s FDA-approved for the treatment of narcolepsy, shift work sleep disorder, and obstructive sleep apnea. It doesn’t cure the underlying problems; instead, it helps to alleviate excessive daytime tiredness associated with all three illnesses.

Modafinil’s mechanism of action is unknown, but it is thought to improve the synthesis of several neurotransmitters including serotonin, histamine, norepinephrine, glutamate, and dopamine.

In the late 1990s, Modafinil began to be used off-label as a cognitive enhancer.

Modafinil side effects

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Is there any negative impact from taking a typical Modafinil dosage? To be effective, a smart drug — or any pharmaceutical — must provide significant advantages over disadvantages.

Fortunately, Modafinil has one of the best safety records of any pharmaceutical drug in its class. The typical side effects of Modafinil include:

  • Headache
  • Nausea
  • Anxiety
  • Difficulty sleeping
  • Dizziness
  • Dry mouth/eyes

The bad news is that these unfavorable effects are typically mild, and when they do occur, they are brief in duration. Furthermore, correction is generally simple and often effective (e.g., for dehydration, simply drink more water than usual).

Modafinil dosage guide

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Everyone will ultimately go through their own individual “Modafinil dosing” journey, but the end goal remains the same:

Use the following chart to find the correct Modafinil dosage for achieving the greatest degree of cognitive boosting for the desired length of time while reducing the risk of negative effects.

But this brings up two main questions:

1. What Modafinil dosage should I start at?

2. What criteria should I use to determine if I increase or decrease my dosage of Modafinil?

Of course, we’re not authorized to dispense medical advice, but we can speak from our experience — so

take this with a grain of salt.

For the first question, good results have been observed when Modafinil was administered at a dose of 100 mg. To avoid Modafinil interfering with our regular sleep patterns, we take it early in the morning, no later than 9 a.m. However, please keep in mind that these are only my subjective impressions after using this product for almost one year and frequent use of other Nootropics).

(NOTE: It’s important to avoid taking any drugs other than Modafinil, or making significant changes to your usual routine. Otherwise, this could compromise results).

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We’ll generally administer each dose 2-3 times per week, with at least 48 hours between doses. We consider it critical to track how you feel while on Modafinil and detect any adverse effects.

For the first week, we increased the dose by 25mg every Sunday after the initial 100mg because we didn’t feel overstimulated and had no adverse effects. We would then repeat this procedure, re-evaluating on a weekly basis after each increase.

We would decrease the dose by 25 mg every week when experiencing negative symptoms or feeling over-stimulated. We would also evaluate how lowering the Modafinil dosage had affected our well-being and cognitive function.

Standard prescription Modafinil dose?

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The amount of Modafinil that is appropriate for you will not always match the drug’s recommended dosage.

Modafinil is contraindicated in pregnancy and while breastfeeding. The FDA product monograph claims that it’s used at 200mg per day for all of its authorized indications, either in the morning or one hour before beginning a work shift. Here’s why:

“Doses up to 400mg/day, given as a single dose, have been well-tolerated, although there is no clear evidence that this amount extends any further benefits than the 200mg dose.”

Modafinil pills are frequently yellow, orange, white, or black and have either a hundred milligrams (mg) or 200 mg of Modafinil inside. Some persons discover that a lesser dose of Modafinil is more than they can manage without becoming overwhelmed.

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Overall, the majority of the literature and research concludes that a Modafinil dose of 200 mg is ideal for most people — especially novices taking the pharmaceutical pill as a cognitive enhancer.

However, keep in mind that while 400 mg of Modafinil is a typical dosage for physicians, it might lead to more severe side effects like anxiety and nausea in some people.

Develop your personal dosing

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If you’re interested in Modafinil or want to experiment with different dosages, here are a few things we’ve discovered while trying various dosing methods:

Modafinil dosage of 50mg

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We noticed a modest boost in cognitive performance for us, which only lasted 2-3 hours.

Taking 50mg of Modafinil four to six days a week, as opposed to the two to three days per week needed when taking 100-200mg at a time, appears to be feasible.

There were no negative effects at this dose of Modafinil, according to users.

However, as a general guideline, we would think most users would not benefit from starting at this low dosage unless they’ve previously been excessively sensitive to stimulants.

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“I take 60 mg of Modafinil twice a day, but I’m not completely satisfied. My doctor advised me to try half that amount.” Individuals who do extremely well on a smaller dose of Modafinil, according to one Reddit user’s testimonial, are those who can go about their daily lives without being concerned about the world around them.

“50mg works best for me, by far. I’d get overly stimulated for a few hours, have a headache, and then crash and feel awful for the rest of the day when I took 100-200mg.

“After having my coffee, I take 400mg every four hours for safety.”

Modafinil dosage of 100mg

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A 100mg Modafinil dosage may be perfect for when we need enhanced concentration during a typical “9-5” working day.

According to this new information, 100 milligrams of Modafinil seems to be sufficient for most people to observe significant improvements in cognitive function.

We noticed that the boost in cognitive enhance is lost after 7-8 hours when using Modafinil, due to its 12-15 hour half-life.

A few team members, on the other hand, prefer splitting their daily Modafinil dose of 100mg into two separate doses: 50mg at 7-8 am and 50mg at 12-1 pm.

If you don’t notice an improvement in your attention after taking this amount of Modafinil, keep reading.

Modafinil dosage of 200mg

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This is the typical dosage taken by most Modafinil users who are serious about improving their energy and attention throughout the day.

It’s also the most “well-researched” dose of Modafinil, and it’s expressly suggested in the product monograph for people who have been given Modafinil:

“The stated starting daily dose is 200mg. The entire daily dose may be taken as a single dose in the morning or as two doses, one in the morning and one at noon, according to the patient’s response and physician assessment of the patient.”

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At 200mg of Modafinil, we found that most people experience all of the cognitive effects they desire with little to no negative side effects.

We discovered that most Modafinil users were able to achieve positive results at 1-3 days per week with this dosage. There does not appear to be much scientific evidence to suggest that exceeding 200mg of Modafinil provides any additional benefits, or that dividing your dose into two 100mg segments makes any difference.

We wouldn’t take a 300mg Modafinil dose unless we absolutely need more than 1-2 hours of concentration, or expect to stay awake for more than 24 hours.

Even taking this dose before 9 a.m. has resulted in difficulty sleeping before 3-4 a.m., and we’ve woken up feeling “slightly hungover.”

Although this Modafinil dosage has not been extensively researched in the literature, several of the research findings are consistent with facts.

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According to one research, using 300 milligrams of Modafinil to power through sleep loss reduced performance the next day:

“During overnight job performance, enhanced efficiency was observed with Modafinil at various dosages (200 mg vs. 100 mg; 300, 400 mg vs. 200, 100 mg). The greatest dosage, on the other hand (300 mg) reduced the effect by disrupting prior sleep. ”

However, in another study, Modafinil was given to French military personnel who had been deprived of sleep for 64 hours at 300 mg.

If you choose to take this dosage of Modafinil, consider splitting the daily dose into two smaller doses: 150mg in the early morning and 150mg about an hour after lunch.

Microdosing Modafinil

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Taking 1/5th to 1/10th of the normal Modafinil dosage is referred to as “Modafinil microdosing.” A microdose of Modafinil would be 50mg or less in practice.

Many persons who believe that a Modafinil dose of 100mg is “too much” may discover smaller dosages to be more tolerable. They can still reap the benefits of Modafinil without any adverse effects.

One user in a Reddit discussion on the advantages of microdosing Modafinil claimed that they were able to get by on 12.5mg of Modafinil per day:

“There are no residual effects with the microdoses, and successive day usages tend to be more effective. Bottom line: My own experience is that this stuff has almost saved me by allowing me to work continuously and productively for an extended period of time with focus.

Microdosing Modafinil may also be beneficial for those who have liver issues or are 65 years of age or older.

If you’re just getting started with Modafinil and want to gradually increase your dosage, one smart drug user recommended a suggested schedule that helps them reach 70mg of Modafinil per day:

  • Days 1-3: Take 25mg of Modafinil at the same time each day
  • Days 4-6: Three-day break
  • Days 7-9: Take 50mg of Modafinil at the same time each day
  • Days 10-12: Three-day break

You’d follow a “three days on, three days off” routine with progressively higher doses until you discovered your ideal Modafinil dosage.

Conclusion

If you’re new to Modafinil and just want to gradually increase your dose, one smart drug user recommended a suggested regimen that helped them get to 70mg of Modafinil each day:

Days 1-3: Take 25mg of Modafinil at the same time each day

Days 4-6: Three-day break

Days 7-9: Take 50mg of Modafinil at the same time each day

Days 10-12: Three-day break

You’d use a “three days on, three days off” regimen with progressively higher dosages until you found your ideal Modafinil dosage.

FAQ’s

Can I take 400 mg Modafinil?

There is no evidence that taking a 400mg Modafinil dosage provides any additional benefits.

Is 200 mg of Modafinil too much?

No, 200mg of Modafinil is not too much for most people. It provides all the cognitive effects they desire with little to no negative side effects.

What strengths does Modafinil come in?

Modafinil is available in 100mg, 200mg, and 300mg dosages.

Can you take 400 mg of Modafinil?

There is no evidence that taking a 400mg Modafinil dosage provides any additional benefits.

How long does 100mg Modafinil last?

100mg of Modafinil lasts about 12 hours.

Resources

  1. https://www.rxlist.com/provigil-drug.htm
  2. https://www.pdr.net/drug-summary/Provigil-modafinil-2332
  3. https://www.drugs.com/dosage/modafinil.html
  4. https://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details
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